Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 9/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640235 | 0.94 | SIGMAR1 (0.37) | CXCR4MEN1KMT2ASIGMAR1DUT | |
| SCHEMBL14855784 | 0.83 | PSMB1 (0.42) | HRH3MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL1309385 | 0.81 | CXCR4 (0.45) | CXCR4HRH3HRH2HRH1MEN1 | |
| SCHEMBL29683731 | 0.76 | SIGMAR1 (0.33) | SIGMAR1DUTPOLBSMN1; SMN2 | |
| SCHEMBL23486745 | 0.75 | DUT (0.39) | DUTSMN1; SMN2 | |
| SCHEMBL2189051 | 0.74 | CXCR4 (0.57) | CXCR4HRH3HRH2HRH1MEN1 | |
| SCHEMBL22558243 | 0.73 | DUT (0.33) | DUT | |
| SCHEMBL5346493 | 0.73 | ALDH1A1 (0.41) | MEN1KMT2ADUTPOLB | |
| SCHEMBL30123669 | 0.73 | HRH3 (0.46) | HRH3DUT | |
| Hydrochloric Acid SCHEMBL28701161 | 0.73 | CXCR4 (0.55) | CXCR4HRH3HRH2HRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190272-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190272-A1 | CHEMICAL COMPOUNDS | CSF3R, FLT3, CILK1 | CXCR4 987/4885HRH3 496/4885HRH2 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.