SCHEMBL1367290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1366752	0.94	TSHR (0.59)	TSHRTHRBPOLBAPEX1HTT
	SCHEMBL8398429	0.90	TSHR (0.70)	TSHRTHRBPOLBAPEX1HTT
	SCHEMBL41489	0.89	TSHR (0.56)	TSHRTHRBPOLBAPEX1HTT
	SCHEMBL1532875	0.88	THRB (0.52)	TSHRTHRBPOLBAPEX1HTT
	Ammonia Solution, Strong SCHEMBL27661293	0.87	TSHR (0.55)	TSHRTHRBPOLBAPEX1HTT
	Ammonia Solution, Strong SCHEMBL139045	0.87	TSHR (0.55)	TSHRTHRBPOLBAPEX1HTT
	Phosphoric Acid SCHEMBL3464242	0.86	TSHR (0.62)	TSHRTHRBPOLBAPEX1HTT
	SCHEMBL14007299	0.85	TSHR (0.53)	TSHRTHRBPOLBAPEX1HTT
	SCHEMBL22421799	0.85	TSHR (0.53)	TSHRTHRBPOLBAPEX1HTT
	SCHEMBL11843082	0.85	TSHR (0.56)	TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.