Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367290 | 0.94 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL294789 | 0.89 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8398429 | 0.89 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL719879 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16026753 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12504621 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12504625 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15389725 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15389940 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2943884 | 0.87 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123246-B1 | ADHESIVE COMPOSITION FOR DENTAL USE | TOKUYAMA DENTAL CORP (JP) | 2021-06-23 | — | — | EP | disclosed |
| EP-2305205-B1 | DENTAL ADHESIVE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-8796354-B2 | Dental adhesive composition | TOKUYAMA DENTAL CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8546459-B2 | Dental filling/restoration kit | TOKUYAMA DENTAL CORPORATION (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8513327-B2 | Adhesive composition for dental use | TOKUYAMA DENTAL CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| CN-102300545-A | Dental filling repair kit | — | 2011-12-28 | — | — | CN | disclosed |
| US-20110288195-A1 | DENTAL FILLING/RESTORATION KIT | TOKUYAMA DENTAL CORPORATION (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110098375-A1 | DENTAL ADHESIVE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2305205-A1 | DENTAL ADHESIVE COMPOSITION | Tokuyama Dental Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20100317762-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | TOKUYAMA DENTAL CORPORATION | 2010-12-16 | — | — | US | disclosed |
| EP-2123246-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | Tokuyama Dental Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317762-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | ITGA1, VMA21, ITGA6 | TSHR 1077/4885THRB 259/4885POLB 2366/4885 |
| US-20110098375-A1 | DENTAL ADHESIVE COMPOSITION | CAD, CDH1, ITGA4 | TSHR 2496/4885THRB 628/4885POLB 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.