Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21515089 | 0.88 | NAALAD2 (0.60) | NAALAD2TRPV1 | |
| SCHEMBL28504133 | 0.88 | NAALAD2 (0.60) | NAALAD2TRPV1 | |
| Hydrochloric Acid SCHEMBL21494731 | 0.87 | NAALAD2 (0.58) | NAALAD2 | |
| Hydrochloric Acid SCHEMBL28501489 | 0.87 | NAALAD2 (0.58) | NAALAD2 | |
| SCHEMBL23030234 | 0.79 | NAALAD2 (0.47) | NAALAD2ALDH1A1 | |
| SCHEMBL6947622 | 0.73 | NAALAD2 (0.45) | NAALAD2NPC1ALDH1A1RAB9ATRPV1 | |
| Chloromethane SCHEMBL29231841 | 0.72 | NAALAD2 (0.64) | NAALAD2 | |
| Hydrochloric Acid SCHEMBL21494705 | 0.72 | NAALAD2 (0.67) | NAALAD2 | |
| Hydrochloric Acid SCHEMBL21494707 | 0.72 | NAALAD2 (0.67) | NAALAD2 | |
| SCHEMBL24811742 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052587-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | MEDICINSK FORSKNING (SE) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052587-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | IL2, THPO, IL6 | NAALAD2 747/4885NPC1 3778/4885ALDH1A1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.