SCHEMBL2303320

SCHEMBL2303320

Cc1c(Oc2ccccc2)[c]c(Oc2ccccc2)cc1Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.37
LTA4H P09960 2/20 0.37
TSHR P16473 1/20 0.37
BRD4 O60885 1/20 0.36
SLC6A4 P31645 2/20 0.34
RIPK1 Q13546 1/20 0.34
SLC6A2 P23975 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADORA1 P30542 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306847 0.84 LTA4H (0.38) LTA4HTSHRBRD4CYP1A2CYP2C9
SCHEMBL10323072 0.82 LTA4H (0.39) TTRLTA4HTSHRSLC6A4RIPK1
SCHEMBL2302479 0.79 LTA4H (0.33) LTA4HTSHRRIPK1ALDH1A1
SCHEMBL10324445 0.74 LTA4H (0.42) TTRLTA4HTSHRSLC6A4RIPK1
SCHEMBL2302914 0.74 LTA4H (0.46) LTA4HTSHRCYP1A2CYP2C9CYP2C19
SCHEMBL2465788 0.73 LTA4H (0.41) LTA4HTSHRBRD4CYP1A2CYP2C19
SCHEMBL10006897 0.72 LTA4H (0.55) TTRLTA4HTSHRSLC6A4RIPK1
SCHEMBL3331237 0.72 LTA4H (0.44) TTRLTA4HTSHRBRD4SLC6A4
SCHEMBL10324745 0.71 LTA4H (0.48) TTRLTA4HTSHRSLC6A4RIPK1
SCHEMBL2302460 0.70 KDM4E (0.43) LTA4HTSHRCYP1A2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3978537-B1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER UNIV TOKYO (JP) 2023-09-13 EP disclosed
WO-2023033030-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 国立大学法人 東京大学 2023-03-09 WO disclosed
US-20220220239-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER THE UNIVERSITY OF TOKYO (JP) 2022-07-14 US disclosed
CN-113874402-A Polar group-containing olefin copolymer 国立大学法人东京大学 2021-12-31 CN disclosed
WO-2020241715-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER 国立大学法人東京大学 2020-12-03 WO disclosed
EP-3050892-A1 IMINE COMPOUND AND NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2016-08-03 EP disclosed
EP-2351761-B1 NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX JAPAN POLYPROPYLENE CORP (JP) 2015-12-02 EP disclosed
US-8618319-B2 Metal complex and method for producing α-olefin polymer and method for producing α-olefin/(meth)acrylate copolymer using the same JAPAN POLYPROPYLENE CORPORATION (JP) 2013-12-31 US disclosed
US-20110213110-A1 NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2011-09-01 US disclosed
EP-2351761-A1 NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX Japan Polypropylene Corporation (JP) 2011-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110213110-A1 NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME OPRD1, OSTC, COG7 TTR 2229/4885LTA4H 2152/4885TSHR 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.