Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499546 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MGLLCYP3A4 | |
| SCHEMBL4013471 | 0.83 | KMT2A (0.67) | ALDH1A1KMT2AMEN1MGLLCYP3A4 | |
| SCHEMBL23033355 | 0.80 | KMT2A (0.48) | ALDH1A1KMT2AMEN1MGLLCYP3A4 | |
| SCHEMBL17844495 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2AMEN1MGLLCYP3A4 | |
| SCHEMBL29761989 | 0.78 | SLC1A2 (0.69) | ALDH1A1KMT2ACYP3A4CYP3A5MAPK1 | |
| SCHEMBL5688541 | 0.77 | CACNA2D1 (0.60) | KMT2AMEN1MGLLCYP3A4CYP3A5 | |
| SCHEMBL6797094 | 0.77 | KMT2A (0.58) | ALDH1A1KMT2AMEN1MGLLCYP3A4 | |
| SCHEMBL20456121 | 0.77 | KMT2A (0.46) | ALDH1A1KMT2AMEN1MGLLCYP3A4 | |
| SCHEMBL28710689 | 0.77 | KMT2A (0.46) | KMT2AMEN1MGLLCYP3A4CYP3A5 | |
| SCHEMBL23033354 | 0.76 | KMT2A (0.48) | KMT2AMEN1MGLLCYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040963-B2 | Piperazine derivatives for influenza virus inhibitions | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2021-06-22 | — | — | US | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040963-B2 | Piperazine derivatives for influenza virus inhibitions | HAVCR2, BAZ2A, MAVS | ALDH1A1 631/4885KMT2A 1480/4885MEN1 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.