SCHEMBL4013471

SCHEMBL4013471

CC(C)(C)OC(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.67
MEN1 O00255 1/20 0.67
MGLL Q99685 2/20 0.65
MAOB P27338 1/20 0.57
MAPT P10636 3/20 0.56
KDM4E B2RXH2 2/20 0.56
NPSR1 Q6W5P4 2/20 0.56
HPGD P15428 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
ALDH1A1 P00352 3/20 0.55
CACNA2D1 P54289 2/20 0.55
CACNA1B Q00975 2/20 0.55
CACNB1 Q02641 2/20 0.55
CACNA1C Q13936 2/20 0.55
CACNA1H O95180 1/20 0.55
NPC1 O15118 1/20 0.53
GPR119 Q8TDV5 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6797094 0.92 KMT2A (0.58) KMT2AMEN1MGLLMAOBMAPT
SCHEMBL5688541 0.92 CACNA2D1 (0.60) KMT2AMEN1MGLLCYP3A4CYP2D6
SCHEMBL6792134 0.89 OPRD1 (0.63) KMT2AMEN1MGLLMAOBKDM4E
SCHEMBL3805489 0.87 CYP2D6 (0.57) KMT2AMEN1MGLLMAPTCYP2D6
SCHEMBL8115616 0.87 CYP2D6 (0.57) KMT2AMEN1MGLLMAPTCYP2D6
SCHEMBL31023808 0.86 MGLL (0.55) KMT2AMEN1MGLLMAPTCYP3A4
SCHEMBL28714150 0.86 GPR119 (0.50) KMT2AMEN1MGLLMAPTKDM4E
SCHEMBL15101001 0.86 CNR1 (0.49) KMT2AMEN1MGLLMAPTCYP3A4
SCHEMBL17276580 0.86 MGLL (0.64) KMT2AMEN1MGLLMAPTCYP3A4
SCHEMBL1852622 0.86 GLS (0.57) KMT2AMEN1MGLLMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018004-B2 Carbamate compounds and methods of making and using same H. LUNDBECK A/S (DK) 2024-06-25 US disclosed
WO-2024124287-A1 COMPOUNDS FOR TREATING VIRAL INFECTION THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) 2024-06-20 WO disclosed
WO-2024124287-A1 COMPOUNDS FOR TREATING VIRAL INFECTION THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) 2024-06-20 WO disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-11530189-B2 Carbamate compounds and methods of making and using same H. LUNDBECKA/S (DK) 2022-12-20 US disclosed
US-11530189-B2 Carbamate compounds and methods of making and using same H. LUNDBECKA/S (DK) 2022-12-20 US disclosed
CN-107982266-B Carbamate compounds and methods of making and using the same H.隆德贝克有限公司 2021-07-30 CN disclosed
US-20210188793-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME LUNDBECK LA JOLLA RESEARCH CENTER, INC. 2021-06-24 US disclosed
US-20090176792-A1 SUBSTITUTED DIBENZHYDRYLPIPERAZINES AUSPEX PHARMACEUTICALS, INC. (US) 2009-07-09 US disclosed
US-20090176792-A1 SUBSTITUTED DIBENZHYDRYLPIPERAZINES AUSPEX PHARMACEUTICALS, INC. (US) 2009-07-09 US disclosed
US-20090176792-A1 SUBSTITUTED DIBENZHYDRYLPIPERAZINES AUSPEX PHARMACEUTICALS, INC. (US) 2009-07-09 US disclosed
US-5849732-A Phenol compound having antioxidative activity and the process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1998-12-15 US disclosed
CN-1165815-A Phenol compound and process for preparing the same TANABE SEIYAKU CO (JP) 1997-11-26 CN disclosed
EP-0790240-A1 Phenol-derivatives having pharmaceutical activity and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1997-08-20 EP disclosed
US-5304645-A Colored or fluorescent labels BOEHRINGER MANNHEIM GMBH (DE) 1994-04-19 US disclosed
US-4954630-A COLORIMETRIC OR FLUORESCENT ANALYSIS BOEHRINGER MANNHEIM GMBH (DE) 1990-09-04 US disclosed
EP-0209875-B1 RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION Roche Diagnostics GmbH (DE) 1990-08-29 EP disclosed
EP-0209875-A1 Resorufin derivatives and process for their preparation Roche Diagnostics GmbH (DE) 1987-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530189-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 KMT2A 1102/4885MEN1 2626/4885MGLL 54/4885
US-20210188793-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 KMT2A 1102/4885MEN1 2626/4885MGLL 54/4885
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 KMT2A 1102/4885MEN1 2626/4885MGLL 54/4885
US-12018004-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 KMT2A 1102/4885MEN1 2626/4885MGLL 54/4885
US-20090176792-A1 SUBSTITUTED DIBENZHYDRYLPIPERAZINES HRH2, HRH4, HRH1 KMT2A 1721/4885MEN1 4210/4885MGLL 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.