Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UTRN | P46939 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 6/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033949 | 0.85 | ALDH1A1 (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23033647 | 0.82 | MAPT (0.41) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL23033680 | 0.82 | NR2E1 (0.33) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL23033321 | 0.81 | ALDH1A1 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23033956 | 0.79 | KDM4E (0.37) | NPC1RAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23012923 | 0.78 | CASP3 (0.47) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL20469749 | 0.78 | NPC1 (0.48) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL23033324 | 0.78 | PIK3CB (0.37) | CASP3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL23033477 | 0.78 | LMNA (0.38) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL23033969 | 0.77 | ALDH1A1 (0.36) | CASP3SENP8SENP7SENP6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |