Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033324 | 0.93 | PIK3CB (0.37) | LMNANPSR1KMT2ATP53MAPT | |
| SCHEMBL23033321 | 0.88 | ALDH1A1 (0.39) | LMNANPSR1TP53MAPTALDH1A1 | |
| SCHEMBL23033956 | 0.85 | KDM4E (0.37) | LMNANPSR1TP53MAPTALDH1A1 | |
| SCHEMBL23033326 | 0.84 | PTGS2 (0.36) | NPSR1TP53MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23033647 | 0.82 | MAPT (0.41) | NPSR1TP53MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23033680 | 0.81 | NR2E1 (0.33) | LMNANPSR1KMT2ATP53MAPT | |
| SCHEMBL23034044 | 0.78 | ALDH1A1 (0.46) | LMNANPSR1TP53MAPTALDH1A1 | |
| SCHEMBL23033970 | 0.78 | PTGS2 (0.41) | LMNANPSR1TP53MAPTALDH1A1 | |
| SCHEMBL23033960 | 0.78 | CASP3 (0.46) | NPSR1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL23012956 | 0.77 | LMNA (0.42) | LMNANPSR1KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |