Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23035330 | 0.99 | MEN1 (0.44) | KMT2AMEN1TNFFPR2IDO1 | |
| SCHEMBL23922669 | 0.85 | FPR2 (0.38) | KMT2AMEN1TNFFPR2IDO1 | |
| Hydrochloric Acid SCHEMBL28489200 | 0.84 | FPR2 (0.37) | KMT2AMEN1TNFFPR2IDO1 | |
| SCHEMBL16679474 | 0.81 | RAB9A (0.38) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL23035197 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL23035339 | 0.81 | LMNA (0.54) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL23035322 | 0.81 | KMT2A (0.54) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL16679379 | 0.80 | RAB9A (0.52) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL23035307 | 0.80 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL23035297 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742019-B1 | N1-CYCLIC AMINE-N5-SUBSTITUTED PHENYL BIGUANIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | IMMUNOMET THERAPEUTICS INC (US) | 2021-03-03 | — | — | EP | claimed |
| EP-2742019-B1 | N1-CYCLIC AMINE-N5-SUBSTITUTED PHENYL BIGUANIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | IMMUNOMET THERAPEUTICS INC (US) | 2021-03-03 | — | — | EP | disclosed |