SCHEMBL230376

SCHEMBL230376

OCCn1cnc2ccccc21

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.78
▸ EGLN3 Q9H6Z9 1/20 0.65
▸ LMNA P02545 6/20 0.64
▸ SMN1; SMN2 Q16637 5/20 0.64
▸ HTT P42858 3/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ CYP11B1 P15538 3/20 0.58
▸ CYP11B2 P19099 3/20 0.58
▸ TNF P01375 1/20 0.58
▸ TSHR P16473 2/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.57
▸ ALOX15 P16050 1/20 0.57
▸ RAB9A P51151 2/20 0.54
▸ GAA P10253 1/20 0.54
▸ MAPK1 P28482 1/20 0.53
▸ NPC1 O15118 2/20 0.53
▸ PKM P14618 1/20 0.53
▸ GGPS1 O95749 1/20 0.53
▸ FDPS P14324 1/20 0.53
▸ KDM4E B2RXH2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825505 0.89 TDP1 (0.72) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL6442808 0.88 TDP1 (1.00) TDP1EGLN3LMNASMN1; SMN2HTT
Fumaric Acid SCHEMBL4791789 0.87 EGLN3 (0.64) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL5610837 0.87 TDP1 (0.70) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL30058168 0.87 TDP1 (0.70) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL5610799 0.86 TDP1 (0.68) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL14740042 0.86 TDP1 (0.68) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL5888624 0.86 TDP1 (0.68) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL9814242 0.84 TDP1 (0.84) TDP1EGLN3LMNASMN1; SMN2HTT
SCHEMBL3862944 0.84 TDP1 (0.70) TDP1EGLN3LMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872930-A N-substituted 3,4-dihydroisoquinoline-1 (2H) -ketone derivative, composition thereof and application thereof in medicines 贵州医科大学 2023-03-31 — — CN claimed
CN-109354587-A The preparation method and Pantoprazole Sodium of Pantoprazole Sodium 成都天台山制药有限公司 2019-02-19 — — CN claimed
EP-2773378-B1 PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) SELCH LARSEN CLAUS (DK) 2016-08-10 — — EP claimed
US-9139567-B2 Arylpyrazole ethers as inhibitors of leukotriene A4 hydrolase BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-22 — — US claimed
US-20140221373-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-08-07 — — US claimed
EP-2734516-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE Boehringer Ingelheim International GmbH (DE) 2014-05-28 — — EP claimed
WO-2013012844-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-01-24 — — WO claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 — — US claimed
JP-11148008-A — — None — — JP disclosed
US-12612547-B2 Semiconducting nanoparticle SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-28 — — US disclosed
EP-4232518-B1 COMPOSITION SAMSUNG ELECTRONICS CO LTD (KR) 2026-02-18 — — EP disclosed
US-12522714-B2 Polysiloxane composition MERCK PATENT GMBH (DE) 2026-01-13 — — US disclosed
EP-4028485-B1 NEW LIGANDS AND SEMICONDUCTING NANOPARTICLE SAMSUNG ELECTRONICS CO LTD (KR) 2025-12-24 — — EP disclosed
EP-4208904-B1 DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2025-10-29 — — EP disclosed
US-5026629-A Thiosulfate fixing agent; imidazole compound; reduction of retained thiosulfate ion and dye stain EASTMAN KODAK COMPANY (US) 1991-06-25 — — US disclosed
US-4782050-A BACTERICIDES PFIZER INC. (US) 1988-11-01 — — US disclosed
EP-0276942-A1 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof PFIZER INC. (US) 1988-08-03 — — EP disclosed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 — — US disclosed
EP-0150380-A1 Process for the preparation of N-vinylated unsaturated nitrogen-containing five-membered heterocycles BAYER AG (DE) 1985-08-07 — — EP disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612547-B2 Semiconducting nanoparticle SCO2, NAF1, LBR TDP1 4440/4885EGLN3 2959/4885LMNA 1022/4885
US-20140221373-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE LTA4H, LTC4S, LTB4R TDP1 3148/4885EGLN3 414/4885LMNA 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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