Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27350364 | 1.00 | ALDH1A1 (0.47) | ALDH1A1FAAHMCL1MLYCDCES1 | |
| Trifluoroacetic Acid SCHEMBL27762565 | 0.83 | TSHR (0.39) | FAAHMLYCDCES1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL28697978 | 0.82 | DPP4 (0.35) | ALDH1A1FAAHMLYCDCES1MEN1 | |
| Trifluoroacetic Acid SCHEMBL6909668 | 0.80 | FAAH (0.39) | ALDH1A1FAAHCES1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL140346 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL4287600 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL5745817 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL128012 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL1727596 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL3833376 | 0.80 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021444-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021041671-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-03-04 | — | — | WO | disclosed |