Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658021 | 0.76 | RAPGEF4 (0.42) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL27714137 | 0.74 | ALDH1A1 (0.55) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL29112903 | 0.73 | ALDH1A1 (0.48) | SLC2A1MAPTMEN1KMT2AATM | |
| SCHEMBL25385990 | 0.73 | PLA2G1B (0.57) | SLC2A1MAPTMEN1KMT2AATM | |
| SCHEMBL10255934 | 0.73 | MAPT (0.53) | SLC2A1MAPTMEN1KMT2AATM | |
| SCHEMBL27915249 | 0.73 | RAPGEF4 (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10985678 | 0.71 | MAPT (0.52) | SLC2A1MAPTMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL28200074 | 0.71 | RAPGEF4 (0.42) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL9844844 | 0.70 | RAPGEF4 (0.45) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL28391249 | 0.70 | EPHX1 (0.52) | SLC2A1MAPTMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021441-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | Trustees of Dartmouth College (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021042046-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-03-04 | — | — | WO | disclosed |