Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28200074 | 0.98 | RAPGEF4 (0.42) | RAPGEF4RAB9ANPC1SOS1HPGD | |
| Phosphoric Acid SCHEMBL28200726 | 0.88 | RAB9A (0.46) | RAPGEF4RAB9ANPC1SOS1HPGD | |
| Sulfuric Acid SCHEMBL28200761 | 0.88 | SOS1 (0.46) | RAPGEF4RAB9ANPC1SOS1HPGD | |
| Oxalic Acid SCHEMBL28200222 | 0.88 | RAB9A (0.50) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL28658021 | 0.78 | RAPGEF4 (0.42) | RAPGEF4RAB9ANPC1SOS1HPGD | |
| SCHEMBL2119807 | 0.76 | SOS1 (0.61) | RAPGEF4RAB9ANPC1SOS1HPGD | |
| SCHEMBL5841636 | 0.74 | TRPV4 (0.50) | — | |
| SCHEMBL28200778 | 0.74 | RAPGEF4 (0.40) | RAPGEF4CES2CES1 | |
| SCHEMBL23044005 | 0.73 | SLC2A1 (0.53) | RAPGEF4RAB9ANPC1MEN1KMT2A | |
| SCHEMBL12981083 | 0.72 | RAB9A (0.47) | RAPGEF4RAB9ANPC1SOS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-103237800-B | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-10-21 | — | — | CN | disclosed |
| CN-103237800-A | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP | 2013-08-07 | — | — | CN | disclosed |