Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304488 | 0.83 | SCN8A (0.43) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL14145363 | 0.81 | SCN8A (0.42) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL14145336 | 0.81 | SCN8A (0.42) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL23212110 | 0.81 | SCN8A (0.45) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL29950883 | 0.81 | SLC6A9 (0.43) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL1438650 | 0.79 | SCN8A (0.43) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL25511137 | 0.78 | RXRA (0.43) | SCN8ASCN10ALIPGLPLSLC6A9 | |
| SCHEMBL25025001 | 0.76 | MAPT (0.47) | SCN8ASCN10APDE4BLMNAPDE4D | |
| SCHEMBL31053867 | 0.76 | MAPT (0.47) | SCN8ASCN10APDE4BLMNAPDE4D | |
| SCHEMBL6461922 | 0.76 | SIRT1 (0.44) | SIRT1PDE4BPTGDR2PTGER1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021068179-A1 | NOVEL HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-04-15 | — | — | WO | disclosed |