Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057529 | 0.82 | ABL1 (0.37) | MCHR1HCRTR1HCRTR2SMO | |
| SCHEMBL30932106 | 0.82 | ABL1 (0.37) | MCHR1HCRTR1HCRTR2SMO | |
| SCHEMBL23044980 | 0.79 | MCHR1 (0.35) | MCHR1HCRTR1HCRTR2SMO | |
| SCHEMBL30932107 | 0.77 | HCRTR1 (0.33) | HCRTR1HCRTR2CACNA2D1KCNH2CACNA2D2 | |
| SCHEMBL23044952 | 0.77 | HCRTR1 (0.33) | HCRTR1HCRTR2CACNA2D1KCNH2CACNA2D2 | |
| SCHEMBL22129420 | 0.76 | SMO (0.39) | SMO | |
| SCHEMBL30932101 | 0.75 | AR (0.40) | MCHR1CACNA2D1CACNA2D2 | |
| SCHEMBL22153065 | 0.73 | JAK2 (0.36) | KCNH2SMO | |
| SCHEMBL17559324 | 0.71 | GPR119 (0.48) | ACACBPDE10ASMOHRH3 | |
| SCHEMBL22480003 | 0.68 | PPARD (0.43) | FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |