Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.32 |
| ▸ | LIPE | Q05469 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540951 | 0.78 | MCHR1 (0.34) | MCHR1PPARGPPARDPPARAS1PR1 | |
| SCHEMBL23044954 | 0.70 | HCRTR1 (0.34) | HCRTR1HCRTR2MCHR1KDM2BCNR2 | |
| SCHEMBL28535469 | 0.68 | SLC6A4 (0.32) | — | |
| SCHEMBL28427006 | 0.64 | PDE2A (0.38) | MCHR1SMN1; SMN2PDE2A | |
| SCHEMBL23044963 | 0.64 | PDE10A (0.38) | HCRTR1HCRTR2PDE2A | |
| SCHEMBL30932098 | 0.64 | PDE10A (0.38) | HCRTR1HCRTR2PDE2A | |
| SCHEMBL23044952 | 0.64 | HCRTR1 (0.33) | HCRTR1HCRTR2MBOAT4 | |
| SCHEMBL30932107 | 0.64 | HCRTR1 (0.33) | HCRTR1HCRTR2MBOAT4 | |
| SCHEMBL28910792 | 0.63 | KCNH2 (0.42) | MBOAT4MCHR1 | |
| SCHEMBL28422546 | 0.62 | S1PR1 (0.35) | S1PR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |