Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | SMO | Q99835 | 2/20 | 0.31 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057529 | 0.80 | ABL1 (0.37) | MCHR1ABL1HCRTR1HCRTR2SMO | |
| SCHEMBL30932106 | 0.80 | ABL1 (0.37) | MCHR1ABL1HCRTR1HCRTR2SMO | |
| SCHEMBL23044984 | 0.79 | MCHR1 (0.33) | MCHR1HCRTR1HCRTR2SMO | |
| SCHEMBL23044954 | 0.78 | HCRTR1 (0.34) | MCHR1ABL1HCRTR1HCRTR2 | |
| SCHEMBL22129464 | 0.76 | SMO (0.41) | SMO | |
| SCHEMBL30932101 | 0.73 | AR (0.40) | MCHR1 | |
| SCHEMBL22129389 | 0.73 | RET (0.37) | HCRTR1HCRTR2SMO | |
| SCHEMBL28540951 | 0.70 | MCHR1 (0.34) | MCHR1 | |
| SCHEMBL22129474 | 0.66 | PDE10A (0.46) | — | |
| SCHEMBL28547292 | 0.66 | PDE3B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |