SCHEMBL23045148

SCHEMBL23045148

CCCCc1cccc2c1[PH](=O)Oc1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
ELANE P08246 2/20 0.34
CTSG P08311 2/20 0.34
LIPG Q9Y5X9 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A1 P04798 1/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
BID P55957 3/20 0.32
MCL1 Q07820 3/20 0.32
BCL2L1 Q07817 2/20 0.32
BAK1 Q16611 2/20 0.32
KAT8 Q9H7Z6 2/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
EP300 Q09472 1/20 0.32
KAT2A Q92830 1/20 0.32
KAT2B Q92831 1/20 0.32
KAT5 Q92993 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20873668 0.88 PKM (0.32)
SCHEMBL2436459 0.84 NR1H2 (0.35) NR1H2NR1H3ELANECTSGLIPG
SCHEMBL28762610 0.82 FOLH1 (0.31)
SCHEMBL9287075 0.74 NR1H2 (0.40) NR1H2NR1H3ELANECTSGLIPG
SCHEMBL2435895 0.73 MYC (0.36)
SCHEMBL2431079 0.72 GPR3 (0.41) TDP1THRATHRB
SCHEMBL2436972 0.71 NR1H2 (0.37) NR1H2NR1H3ELANECTSGLIPG
SCHEMBL28602601 0.71
SCHEMBL28619413 0.70 MAPK1 (0.32)
SCHEMBL30172459 0.70 HDAC3 (0.35) TDP1THRBMCL1BCL2L1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021039368-A1 TRANSPARENT THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD THEREFOR, MOLDED ARTICLE OBTAINED BY MOLDING TRANSPARENT THERMOPLASTIC RESIN COMPOSITION, AND PRODUCTION METHOD FOR MOLDED ARTICLE 東レ株式会社 2021-03-04 WO disclosed
CN-104610222-A Process for preparing episulfide compounds ASAHI KASEI CHEMICALS CORP 2015-05-13 CN disclosed
CN-103502315-A Composition and polymer ASAHI KASEI CHEMICALS CORP 2014-01-08 CN disclosed
CN-103476764-A Process for producing episulfide compound ASAHI KASEI CHEMICALS CORP (JP) 2013-12-25 CN disclosed