SCHEMBL2431079

SCHEMBL2431079

CCCCc1ccc2c(c1)[PH](=O)Oc1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.41
PSMB5 P28074 1/20 0.35
SKP2 Q13309 1/20 0.35
POLB P06746 1/20 0.33
DHODH Q02127 1/20 0.33
METAP2 P50579 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGES O14684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2434448 0.86 GPR3 (0.38) GPR3PSMB5SKP2POLBDHODH
SCHEMBL2428112 0.86 MAPT (0.46) POLBTHRBALDH1A1SMN1; SMN2NPC1
SCHEMBL2441281 0.77 GPR3 (0.35) GPR3PSMB5SKP2POLBTHRA
SCHEMBL2436802 0.76 CNR1 (0.48)
SCHEMBL2438109 0.75 ELANE (0.42) LMNA
Alcohol SCHEMBL28762611 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL2434428 0.73 NPC1 (0.51) POLBALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL23045148 0.72 NR1H2 (0.37) THRATHRBTDP1
SCHEMBL30781 0.72 HSP90AA1 (0.35) MAPK1TDP1
SCHEMBL29395467 0.72 HSP90AA1 (0.35) MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed