SCHEMBL10909718

SCHEMBL10909718

CN(C)C(=S)SC(=S)[N+](C)(C)S

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.57
ALDH1A1 P00352 3/20 0.57
LMNA P02545 2/20 0.57
HTT P42858 2/20 0.57
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
FAAH O00519 1/20 0.43
JAK2 O60674 1/20 0.43
BBOX1 O75936 1/20 0.43
TP53 P04637 1/20 0.43
ALDH2 P05091 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CYP3A4 P08684 1/20 0.43
FBP1 P09467 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
LOX P28300 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930708 0.78 MGLL (0.62) MGLLALDH1A1LMNAHTTKDM4E
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL23048 0.74 ALDH1A1 (1.00) MGLLALDH1A1LMNAHTTKDM4E
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL28541106 0.72 ALDH1A1 (0.93) MGLLALDH1A1LMNAHTTKDM4E
Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL10909720 0.72 ALDH1A1 (0.93) MGLLALDH1A1LMNAHTTKDM4E
Thiram SCHEMBL23248447 0.66 ALDH1A1 (0.93) MGLLALDH1A1LMNAHTTKDM4E
Thiram SCHEMBL2773352 0.66 ALDH1A1 (0.93) MGLLALDH1A1LMNAHTTKDM4E
Thiram SCHEMBL80195 0.66 ALDH1A1 (0.93) MGLLALDH1A1LMNAHTTKDM4E
Thiram SCHEMBL234787 0.66 ALDH1A1 (0.93) MGLLALDH1A1LMNAHTTKDM4E
SCHEMBL7775454 0.65
SCHEMBL18038521 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4603712-A Compounded polychloroprene formulation used as an adhesive layer in the manufacture of elastomeric articles THE GATES RUBBER COMPANY (US) 1986-08-05 US disclosed