Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.32 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052232 | 1.00 | FAAH (0.34) | FAAHHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23052223 | 0.96 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL29452755 | 0.96 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL23041434 | 0.92 | MME (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23041431 | 0.92 | MME (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29452671 | 0.90 | ALDH1A1 (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL23052279 | 0.90 | ALDH1A1 (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL23052228 | 0.90 | PHGDH (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28722775 | 0.90 | PHGDH (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23051963 | 0.89 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |