Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 3/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052223 | 1.00 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL23052233 | 0.96 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL23052232 | 0.96 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL23052279 | 0.94 | ALDH1A1 (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL29452671 | 0.94 | ALDH1A1 (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB | |
| SCHEMBL28722775 | 0.94 | PHGDH (0.34) | PHGDHAVPR1BPOLBMMEKDM4E | |
| SCHEMBL23052228 | 0.94 | PHGDH (0.34) | PHGDHAVPR1BPOLBMMEKDM4E | |
| SCHEMBL23041524 | 0.91 | MME (0.37) | PHGDHMMEMMEL1 | |
| SCHEMBL23041526 | 0.91 | MME (0.37) | PHGDHMMEMMEL1 | |
| SCHEMBL23051947 | 0.90 | FAAH (0.34) | FAAHPHGDHAVPR1BSLC8A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |