Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13949974 | 0.82 | HDAC1 (1.00) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL857490 | 0.77 | MET (0.59) | HDAC1MTNR1AKMT2AGPR84MET | |
| SCHEMBL23054978 | 0.76 | LTA4H (0.54) | HDAC1MTNR1AHDAC6HDAC3HDAC2 | |
| SCHEMBL857812 | 0.76 | MTNR1A (0.57) | HDAC1MTNR1AKMT2AGPR84MET | |
| SCHEMBL30526532 | 0.74 | MTNR1A (0.64) | HDAC1MTNR1AKMT2AGPR84MET | |
| SCHEMBL23055027 | 0.74 | HDAC3 (0.74) | HDAC1MTNR1AHDAC6HDAC3HDAC2 | |
| SCHEMBL857660 | 0.73 | CYP3A4 (0.63) | MTNR1AKMT2AGPR84MET | |
| SCHEMBL857639 | 0.72 | HTT (0.53) | HDAC1MTNR1AKMT2ANAMPTGPR84 | |
| SCHEMBL23055060 | 0.72 | HDAC1 (0.72) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL25029864 | 0.72 | MTNR1A (0.64) | HDAC1MTNR1AHTR6KMT2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB (SE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060014-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | HDAC1 2/4885MTNR1A 4070/4885HTR6 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.