Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743004 | 0.82 | PPARG (0.54) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL10343408 | 0.80 | PPARG (0.66) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL11287518 | 0.79 | L3MBTL1 (0.55) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL14032198 | 0.79 | PPARG (0.55) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL18737238 | 0.79 | PPARG (0.55) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL8741777 | 0.79 | TUBB4A (0.53) | KMT2ATDP1HIF1ATUBB4ATUBB | |
| SCHEMBL84033 | 0.79 | PPARG (0.53) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL9052230 | 0.78 | TSHR (0.49) | NPSR1 | |
| SCHEMBL758673 | 0.78 | PPARG (0.68) | PPARGPPARDPPARAACHECA1 | |
| SCHEMBL6656697 | 0.77 | PPARG (0.61) | PPARGPPARDPPARAACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044593-A1 | CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | claimed |
| WO-2015035410-A1 | CANCER THERAPY | TRIACT THERAPEUTIC, INC. (US) | 2015-03-12 | — | — | WO | claimed |
| EP-3044593-A1 | CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2961412-A1 | CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2015035410-A1 | CANCER THERAPY | TRIACT THERAPEUTIC, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2014134202-A1 | CANCER THERAPY | TRIACT THERAPEUTICS, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| EP-2349235-A1 | USE OF CATECHOLIC BUTANE DERIVATIVES IN CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010054264-A1 | USE OF CATECHOLIC BUTANE DERIVATIVES IN CANCER THERAPY | TRIACT THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |