Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741805 | 0.88 | TSHR (0.46) | TSHRBLMNPSR1NFKB1JUN | |
| SCHEMBL3127079 | 0.86 | TSHR (0.49) | TSHRCYP3A4NFKB1GAAJUN | |
| SCHEMBL21377287 | 0.78 | TNFSF11 (0.51) | TSHRNPSR1NFKB1GAAJUN | |
| SCHEMBL2305575 | 0.78 | PPARG (0.51) | NPSR1 | |
| SCHEMBL4641223 | 0.77 | NR3C1 (0.73) | TSHRBLMCYP3A4NFKB1GAA | |
| SCHEMBL11603493 | 0.76 | TSHR (0.59) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL8741777 | 0.76 | TUBB4A (0.53) | TSHRBLMNFKB1FOSTTR | |
| SCHEMBL15944091 | 0.75 | LMNA (0.50) | TSHRNFKB1GAAJUNNR3C1 | |
| SCHEMBL1595549 | 0.74 | TSHR (0.65) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL30343472 | 0.74 | TSHR (0.65) | TSHRBLMNPSR1CYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010549-A9 | COMPOUNDS FOR THE SUPPRESSION OF HIV TAT TRANSACTIVATION | — | 1996-06-06 | — | — | WO | disclosed |