Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.45 |
| ▸ | MMP9 | P14780 | 7/20 | 0.45 |
| ▸ | MMP8 | P22894 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 8/20 | 0.37 |
| ▸ | MMP3 | P08254 | 7/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | MMP20 | O60882 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MMP15 | P51511 | 1/20 | 0.36 |
| ▸ | MMP16 | P51512 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.36 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17920203 | 0.88 | MMP9 (0.43) | MMP2MMP9MMP8ALDH1A1MMP1 | |
| SCHEMBL13521930 | 0.88 | MMP9 (0.43) | MMP2MMP9MMP8ALDH1A1MMP1 | |
| SCHEMBL12628471 | 0.88 | MMP9 (0.43) | MMP2MMP9MMP8ALDH1A1MMP1 | |
| SCHEMBL6948928 | 0.86 | ALDH1A1 (0.46) | MMP2MMP9MMP8ALDH1A1MEN1 | |
| SCHEMBL6948920 | 0.86 | ALDH1A1 (0.46) | MMP2MMP9MMP8ALDH1A1MEN1 | |
| SCHEMBL8201292 | 0.86 | ALDH1A1 (0.46) | MMP2MMP9MMP8ALDH1A1MEN1 | |
| SCHEMBL21895901 | 0.83 | CACNA1B (0.40) | MMP2MMP9MMP8ALDH1A1LMNA | |
| SCHEMBL21895921 | 0.82 | MMP2 (0.58) | MMP2MMP9MMP8ALDH1A1MMP1 | |
| SCHEMBL12226978 | 0.81 | MMP9 (0.51) | MMP2MMP9MMP8ALDH1A1MMP1 | |
| SCHEMBL13833235 | 0.81 | MMP9 (0.51) | MMP2MMP9MMP8ALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | MMP2 1620/4885MMP9 1282/4885MMP8 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.