Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948920 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL8201292 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL17305536 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL30522096 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL23056463 | 0.86 | MMP2 (0.45) | ALDH1A1MEN1LMNAKMT2AMMP2 | |
| SCHEMBL12058749 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL29372296 | 0.82 | OPRM1 (0.46) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL31634304 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL17305535 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL31116669 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1LMNAKMT2AMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956033-B1 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | UNIV ILLINOIS (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6380156-B1 | HAVING ANTIVIRAL, ANTITUMOR, AND IMMUNOSUPPRESSIVE ACTIVITIES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLNOIS | 2002-04-30 | — | — | US | disclosed |
| WO-1998017302-A9 | TOTAL SYNTHESIS OF THE AMINO HIP ANALOGUE OF DIDEMNIN A | — | 1998-10-15 | — | — | WO | disclosed |