Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057332 | 0.87 | ALDH1A1 (0.39) | GAAMAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL23057084 | 0.85 | L3MBTL1 (0.43) | GAAMAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL23057120 | 0.82 | MEN1 (0.53) | GAAMAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL23057051 | 0.82 | L3MBTL1 (0.43) | GAAMAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL23057209 | 0.82 | L3MBTL1 (0.45) | GAAMAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL23057240 | 0.81 | L3MBTL1 (0.40) | GAAMAPTL3MBTL1NPSR1ADRA1A | |
| SCHEMBL23057337 | 0.81 | HRH3 (0.39) | GAAMAPTL3MBTL1NPSR1ADRA1A | |
| SCHEMBL23057265 | 0.80 | MEN1 (0.53) | GAAMAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL23057203 | 0.80 | MAPK1 (0.45) | GAAMAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL23057136 | 0.80 | KEAP1 (0.41) | GAAMAPTL3MBTL1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |