Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | UQCRB | P14927 | 2/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176595 | 0.89 | ALDH1A1 (0.66) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL5965425 | 0.76 | KEAP1 (0.67) | GAAALDH1A1HTTKMT2AL3MBTL1 | |
| SCHEMBL7572310 | 0.76 | ALDH1A1 (0.66) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL1348234 | 0.76 | LMNA (0.75) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL5307424 | 0.74 | EP300 (0.83) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL7579231 | 0.73 | GAA (0.54) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL7570770 | 0.72 | GAA (0.61) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL2069805 | 0.72 | LMNA (0.84) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL7085112 | 0.71 | GAA (0.75) | GAAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL6296987 | 0.71 | GAA (0.93) | GAAALDH1A1HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |