Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | UQCRB | P14927 | 2/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572310 | 0.87 | ALDH1A1 (0.66) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL7570770 | 0.87 | GAA (0.61) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL7579848 | 0.83 | GAA (0.50) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL7570701 | 0.82 | PTGES2 (0.60) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL7572304 | 0.79 | PTGES2 (0.60) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL7574025 | 0.79 | FFAR4 (0.56) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL23057258 | 0.75 | ALDH1A1 (0.73) | GAAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL7176595 | 0.74 | ALDH1A1 (0.66) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL6807397 | 0.74 | KMT2A (0.61) | GAAMAPTHTTMEN1MAPK1 | |
| SCHEMBL7578819 | 0.74 | MEN1 (0.63) | GAAMEN1KMT2AHSD17B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |