Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | C5 | P01031 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14245091 | 0.81 | HTT (0.49) | HTTALOX5IDO1LMNASMN1; SMN2 | |
| SCHEMBL16105088 | 0.81 | HTT (0.59) | HTTALOX5LMNASMN1; SMN2PPIA | |
| SCHEMBL9787495 | 0.77 | HTT (0.58) | HTTALOX5LMNASMN1; SMN2PPIA | |
| SCHEMBL7133337 | 0.75 | ALOX5 (0.43) | HTTALOX5IDO1LMNASMN1; SMN2 | |
| SCHEMBL27490530 | 0.75 | HTR7 (0.49) | HTTALOX5LMNASMN1; SMN2TLR8 | |
| SCHEMBL6890323 | 0.75 | LMNA (0.61) | LMNASMN1; SMN2MAPTNPSR1ALDH1A1 | |
| SCHEMBL991728 | 0.75 | HTT (0.47) | HTTALOX5IDO1LMNASMN1; SMN2 | |
| SCHEMBL27459272 | 0.72 | HTR7 (0.51) | IDO1LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27434096 | 0.72 | HTT (0.44) | HTTALOX5IDO1LMNASMN1; SMN2 | |
| SCHEMBL385728 | 0.72 | HTT (0.70) | HTTIDO1SMN1; SMN2MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350179-A1 | COMPOSITES COMPRISING BIOLOGICALLY-SYNTHESIZED NANOMATERIALS | University Of Houston (US) | 2011-08-03 | — | — | EP | claimed |
| WO-2010062717-A1 | COMPOSITES COMPRISING BIOLOGICALLY-SYNTHESIZED NANOMATERIALS | UNIVERSITY OF HOUSTON (US) | 2010-06-03 | — | — | WO | claimed |