Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 8/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 8/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.45 |
| ▸ | CDK2 | P24941 | 7/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25860 | 0.80 | PDPK1 (0.53) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL29384383 | 0.80 | PDPK1 (0.53) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL1074970 | 0.80 | POLA1 (0.57) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL2306213 | 0.79 | CDK1 (0.32) | POLA1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL30610405 | 0.78 | CDK1 (0.53) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL29514836 | 0.77 | PDPK1 (0.56) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL29592683 | 0.77 | PDPK1 (0.59) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL1982409 | 0.76 | PDPK1 (0.51) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL2402087 | 0.76 | PDPK1 (0.51) | POLA1PDPK1GDACDK1CCNB1 | |
| SCHEMBL30150749 | 0.73 | PDPK1 (0.51) | POLA1PDPK1GDACDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349315-A1 | REGULATION OF LYMPHOCYTES AND USES THEREFOR | University of Miami (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010042697-A1 | REGULATION OF LYMPHOCYTES AND USES THEREFOR | UNIVERSITY OF MIAMI (US) | 2010-04-15 | — | — | WO | disclosed |