SCHEMBL29384383

SCHEMBL29384383

CC(N)Cc1nc(N)c2[nH]cnc2n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.53
GDA Q9Y2T3 1/20 0.53
CDK2 P24941 10/20 0.44
CDK1 P06493 9/20 0.44
CCNB1 P14635 9/20 0.44
CCNA2 P20248 9/20 0.44
CCNA1 P78396 9/20 0.44
PI4KA P42356 2/20 0.42
PI4K2B Q8TCG2 2/20 0.42
PI4K2A Q9BTU6 2/20 0.42
PI4KB Q9UBF8 2/20 0.42
LMNA P02545 1/20 0.42
DRD3 P35462 1/20 0.42
XDH P47989 1/20 0.42
LRRK2 Q5S007 1/20 0.42
POLA1 P09884 1/20 0.40
MAP3K5 Q99683 1/20 0.40
DPP4 P27487 1/20 0.39
PIN1 Q13526 1/20 0.38
PNP P00491 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25860 1.00 PDPK1 (0.53) PDPK1GDACDK2CDK1CCNB1
SCHEMBL1982409 0.86 PDPK1 (0.51) PDPK1GDACDK2CDK1CCNB1
SCHEMBL2402087 0.86 PDPK1 (0.51) PDPK1GDACDK2CDK1CCNB1
SCHEMBL28144662 0.81 PDPK1 (0.46) PDPK1GDACDK2CDK1CCNB1
SCHEMBL2306216 0.80 POLA1 (0.46) PDPK1GDACDK2CDK1CCNB1
SCHEMBL1924592 0.80 PDPK1 (0.59) PDPK1GDACDK2CDK1CCNB1
SCHEMBL29592683 0.80 PDPK1 (0.59) PDPK1GDACDK2CDK1CCNB1
SCHEMBL30150749 0.80 PDPK1 (0.51) PDPK1GDACDK2CDK1CCNB1
SCHEMBL19840 0.80 PDPK1 (0.51) PDPK1GDACDK2CDK1CCNB1
SCHEMBL16753033 0.80 PNP (0.36) PDPK1GDACDK2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025041085-A1 DUAL NUCLEASE SYSTEMS FOR GENE EDITING, METHODS OF PRODUCING AND USING SAME SPECIFIC BIOLOGICS INC. (CA) 2025-02-27 WO claimed
EP-4240839-A1 GENE EDITING WITH A MODIFIED ENDONUCLEASE Specific Biologics Inc. (CA) 2023-09-13 EP claimed
EP-4041249-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES The Scripps Research Institute (US) 2022-08-17 EP claimed
WO-2022097070-A1 GENE EDITING WITH A MODIFIED ENDONUCLEASE SPECIFIC BIOLOGICS INC. (CA) 2022-05-12 WO claimed
EP-4743576-A1 RNA-EDITING OLIGONUCLEOTIDES AND USES THEREOF Korro Bio, Inc. (US) 2026-05-20 EP disclosed
EP-4713459-A2 ANTI-VISTA ANTIBODY RNA OR NUCLEIC ACID CONJUGATES (ARCS OR ANCS), COMPOSITIONS CONTAINING, AND THERAPEUTIC USE THEREOF LIFORDI IMMUNOTHERAPEUTICS, INC. (US) 2026-03-25 EP disclosed
EP-4704906-A2 APTAMER-BASED SUSTAINED RELEASE OF THERAPEUTIC AGENTS The Children's Medical Center Corporation (US) 2026-03-11 EP disclosed
US-12565656-B2 Modulators and modulation of the receptor for advanced glycation end-products RNA MONASH UNIVERSITY (AU) 2026-03-03 US disclosed
EP-4695398-A1 FORMULATIONS FOR OLIGONUCLEOTIDE DELIVERY Alnylam Pharmaceuticals, Inc. (US) 2026-02-18 EP disclosed
EP-4683674-A1 COMPOSITIONS AND METHODS FOR DELIVERING ANTIBODY OLIGONUCLEOTIDE CONJUGATES FOR EXON SKIPPING Yale University (US) 2026-01-28 EP disclosed
EP-4665854-A1 TRANSLATION ENHANCING NUCLEIC ACID COMPOUNDS: ASO COUPLED TRANSLATION - UPREGULATION 1 (ACT-UP1) AND USES THEREOF Arnatar Therapeutics, Inc (US) 2025-12-24 EP disclosed
EP-4662318-A1 PIKFYVE ANTISENSE OLIGONUCLEOTIDES AcuraStem Incorporated (US) 2025-12-17 EP disclosed
WO-2022067398-A1 TREATMENT OF OPTIC ATROPHY PYC Therapeutics Limited (AU) 2022-04-07 WO disclosed
EP-3976791-A1 COMPOUNDS AND METHODS FOR REDUCING FUS EXPRESSION Ionis Pharmaceuticals, Inc. (US) 2022-04-06 EP disclosed
WO-2022066956-A1 COMPOUNDS AND METHODS FOR REDUCING APOE EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2022-03-31 WO disclosed
EP-3969469-A1 ANTISENSE OLIGONUCLEOTIDES TARGETING SCN2A RETAINED INTRONS The Florey Institute of Neuroscience and Mental Health (AU) 2022-03-23 EP disclosed
EP-3969588-A1 COMPOSITIONS AND METHODS FOR TREATING HEPATITIS B VIRUS (HBV) INFECTION VIR Biotechnology, Inc. (US) 2022-03-23 EP disclosed
EP-3963077-A1 TREATMENT FOR SOD1 ASSOCIATED DISEASE Black Swan Pharmaceuticals, Inc. (US) 2022-03-09 EP disclosed
EP-3955966-A1 COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY Sarepta Therapeutics, Inc. (US) 2022-02-23 EP disclosed
EP-3946629-A1 THERAPEUTIC TARGETS FOR ONCOGENIC KRAS-DEPENDENT CANCERS University Of Massachusetts (US) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565656-B2 Modulators and modulation of the receptor for advanced glycation end-products RNA AGER, RNMT, UPF1 PDPK1 4549/4885GDA 582/4885CDK2 4047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.