Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 3/20 | 0.31 |
| ▸ | IDUA | P35475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824034 | 0.79 | FOLH1 (0.45) | FOLH1 | |
| SCHEMBL1824031 | 0.79 | FOLH1 (0.45) | FOLH1 | |
| SCHEMBL30361214 | 0.78 | FOLH1 (0.41) | FOLH1ALB | |
| SCHEMBL8594034 | 0.77 | MME (0.42) | FOLH1 | |
| SCHEMBL13448062 | 0.73 | FOLH1 (0.39) | FOLH1ALBIDUA | |
| SCHEMBL16446180 | 0.73 | FOLH1 (0.39) | FOLH1ALBIDUA | |
| SCHEMBL38654695 | 0.72 | C3AR1 (0.45) | FOLH1ITGB1 | |
| SCHEMBL29631981 | 0.71 | KDM4E (0.42) | FOLH1 | |
| SCHEMBL31549503 | 0.71 | TGFBR1 (0.37) | — | |
| SCHEMBL29024437 | 0.71 | KMT2A (0.43) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334760-B1 | CAPPED AND UNCAPPED ANTIBODY CYSTEINES, AND THEIR USE IN ANTIBODY-DRUG CONJUGATION | PFIZER (US) | 2021-03-10 | — | — | EP | claimed |