SCHEMBL29631981

SCHEMBL29631981

O=C(O)[C@H](CS)NN1C(=O)C=CC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
NFKB1 P19838 1/20 0.42
PTGS2 P35354 1/20 0.42
THPO P40225 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ACE P12821 1/20 0.39
FNTA P49354 2/20 0.37
FNTB P49356 2/20 0.37
FOLH1 Q04609 2/20 0.37
CA1 P00915 4/20 0.36
CA2 P00918 4/20 0.36
MME P08473 3/20 0.35
CPA3 P15088 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31549503 0.85 TGFBR1 (0.37) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL29024583 0.83 MME (0.38) MAPTPTGS2RECQLSMN1; SMN2CA1
SCHEMBL6671437 0.83
SCHEMBL11360473 0.81 ALDH1A1 (0.47) KDM4EMAPTNFKB1PTGS2FNTA
SCHEMBL8829463 0.79 KDM4E (0.46) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL29024434 0.78 MME (0.49) FOLH1MMECPA3
SCHEMBL8594034 0.78 MME (0.42) PTGS2ACEFOLH1CA2MME
SCHEMBL29024437 0.78 KMT2A (0.43) ALOX15BLMFOLH1CA1CA2
SCHEMBL1824031 0.76 FOLH1 (0.45) ACEFOLH1CA1CA2
SCHEMBL28915273 0.76 KDM4E (0.37) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587063-A1 ANTI-MUC1* ANTIBODY DRUG COMPLEXES AND USES THEREOF Minerva Biotechnologies Corporation (US) 2025-07-23 EP disclosed
WO-2025080693-A1 ANTI-MUC1* ANTIBODY DRUG COMPLEXES AND USES THEREOF MINERVA BIOTECHNOLOGIES CORPORATION (US) 2025-04-17 WO disclosed
WO-2022086957-A1 PEG-CONJUGATED ANTI-MERTK ANTIBODIES AND METHODS OF USE GENENTECH, INC. (US) 2022-04-28 WO disclosed