Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824034 | 0.83 | FOLH1 (0.45) | CA2ACEFOLH1 | |
| SCHEMBL1824031 | 0.83 | FOLH1 (0.45) | CA2ACEFOLH1 | |
| SCHEMBL38654695 | 0.79 | C3AR1 (0.45) | FOLH1 | |
| SCHEMBL29631981 | 0.78 | KDM4E (0.42) | MMECA2ACEFOLH1PTGS2 | |
| SCHEMBL31549503 | 0.78 | TGFBR1 (0.37) | MMECA2PTGS1PTGS2 | |
| SCHEMBL29024437 | 0.77 | KMT2A (0.43) | CA2FOLH1 | |
| SCHEMBL23064407 | 0.77 | FOLH1 (0.40) | FOLH1 | |
| SCHEMBL29024583 | 0.76 | MME (0.38) | MMECA2PTGS1PTGS2 | |
| SCHEMBL3517842 | 0.75 | MME (0.52) | MMECA2NOD1ACEFOLH1 | |
| SCHEMBL3517847 | 0.74 | NOD1 (0.52) | MMECA2NOD1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998059242-A1 | HOMOCYSTEINE ASSAY | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | WO | disclosed |