Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24089953 | 0.89 | USP2 (0.40) | ALDH1A1ALDH1A2ALDH1A3MAT2AUSP2 | |
| SCHEMBL24090085 | 0.85 | ALDH1A1 (0.42) | ALDH1A1ALDH1A2ALDH1A3POLBUSP2 | |
| SCHEMBL29623155 | 0.80 | TDO2 (0.50) | MAT2APOLBUSP2MAPTTDO2 | |
| SCHEMBL23045334 | 0.80 | TDO2 (0.50) | MAT2APOLBUSP2MAPTTDO2 | |
| SCHEMBL30103287 | 0.80 | PIK3CD (0.41) | ALDH1A1ALDH1A2ALDH1A3MAPTL3MBTL1 | |
| SCHEMBL24111001 | 0.80 | PIK3CD (0.41) | ALDH1A1ALDH1A2ALDH1A3MAPTL3MBTL1 | |
| SCHEMBL23958176 | 0.77 | ALPL (0.39) | ALDH1A1ALDH1A2ALDH1A3POLBUSP2 | |
| SCHEMBL23958194 | 0.74 | TDO2 (0.46) | MAT2APOLBUSP2MAPTTDO2 | |
| SCHEMBL23958356 | 0.74 | ALOX12 (0.48) | MAPTKDM4E | |
| SCHEMBL23958281 | 0.73 | TDO2 (0.46) | MAT2APOLBL3MBTL1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039968-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | 大日本住友製薬株式会社 | 2021-03-04 | — | — | WO | disclosed |