Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.54 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22155019 | 0.82 | SMARCA2 (0.69) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL4733237 | 0.81 | KMT2A (0.54) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL17059591 | 0.81 | DDX3X (0.60) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL17664185 | 0.80 | KDR (0.67) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL5597699 | 0.80 | KMT2A (0.90) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL30101230 | 0.80 | KMT2A (0.90) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL1464168 | 0.80 | KMT2A (0.69) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL4733239 | 0.80 | KDR (0.54) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL4548162 | 0.78 | KMT2A (0.87) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL17059588 | 0.78 | EGFR (0.61) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021042022-A1 | SEPTIN INHIBITORS FOR TREATMENT OF CANCERS | UNIVERSITY OF ROCHESTER (US) | 2021-03-04 | — | — | WO | disclosed |