Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970538 | 0.78 | MEN1 (0.49) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL28969335 | 0.78 | MEN1 (0.46) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL8385965 | 0.78 | MEN1 (0.44) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL18418870 | 0.77 | PKM (0.42) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL2521727 | 0.76 | MEN1 (0.48) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL14800866 | 0.76 | MEN1 (0.43) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL18366033 | 0.76 | POLB (0.43) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL27849208 | 0.76 | PKM (0.41) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL31319739 | 0.76 | PKM (0.41) | PKMMEN1KMT2AGAAKDM4E | |
| SCHEMBL5106132 | 0.73 | KDM4E (0.43) | PKMMEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341134-B | Process for preparing a medicament comprising an epoxyhexane ring | 豪夫迈·罗氏有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-4028396-B1 | PROCESS FOR THE PREPARATION OF A MEDICAMENT CONTAINING AN OXEPANE RING. | HOFFMANN LA ROCHE (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-11414412-B2 | Process for the preparation of a medicament | GENENTECH, INC. | 2022-08-16 | — | — | US | disclosed |
| CN-114341134-A | Process for the preparation of medicaments comprising an epoxyhexane ring | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20210070749-A1 | PROCESS FOR THE PREPARATION OF A MEDICAMENT | GENENTECH, INC. (US) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070749-A1 | PROCESS FOR THE PREPARATION OF A MEDICAMENT | NEFM, ADRM1, TPMT | PKM 769/4885MEN1 2761/4885KMT2A 3288/4885 |
| US-11414412-B2 | Process for the preparation of a medicament | HNMT, MLNR, SLC10A2 | PKM 1074/4885MEN1 469/4885KMT2A 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.