Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HK2 | P52789 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29687718 | 0.84 | CTSS (0.44) | MAPT | |
| SCHEMBL5384282 | 0.81 | FNTA (0.39) | FNTAFNTBKMT2AKDM4EESR2 | |
| SCHEMBL28731419 | 0.76 | KDM4E (0.33) | KMT2AKDM4EESR2ALDH1A1ADORA3 | |
| SCHEMBL3467175 | 0.73 | SLC7A5 (0.54) | KMT2AKDM4EALDH1A1ADORA3PTGS2 | |
| SCHEMBL3467173 | 0.73 | SLC7A5 (0.54) | KMT2AKDM4EALDH1A1ADORA3PTGS2 | |
| SCHEMBL23067398 | 0.71 | AOC2 (0.41) | KMT2AKDM4EESR2ALDH1A1ADORA3 | |
| SCHEMBL18262789 | 0.71 | KMT2A (0.51) | KMT2AALDH1A1POLBNPSR1GNPAT | |
| SCHEMBL18262792 | 0.71 | KMT2A (0.51) | KMT2AALDH1A1POLBNPSR1GNPAT | |
| SCHEMBL3782261 | 0.69 | KMT2A (0.66) | KMT2AKDM4EMEN1LMNAMAPT | |
| SCHEMBL23067414 | 0.69 | GAA (0.46) | KDM4EALDH1A1CYP3A4CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028404-A2 | PENAM DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | Tennor Therapeutics Limited (CN) | 2022-07-20 | — | — | EP | disclosed |
| US-11040987-B2 | Penam derivatives for treating bacterial infections | TENNOR THERAPEUTICS LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| WO-2021048613-A2 | PENAM DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | TENNOR THERAPEUTICS LIMITED (CN) | 2021-03-18 | — | — | WO | disclosed |
| US-20210070774-A1 | PENAM DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | TENNOR THERAPEUTICS LIMITED (CN) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070774-A1 | PENAM DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | BPGM, BLVRB, PREP | FNTA 381/4885FNTB 138/4885KMT2A 1018/4885 |
| US-11040987-B2 | Penam derivatives for treating bacterial infections | BPGM, BLVRB, PREP | FNTA 381/4885FNTB 138/4885KMT2A 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.