Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733746 | 0.85 | SMO (0.33) | HRH3 | |
| SCHEMBL2304480 | 0.81 | P2RX7 (0.38) | NOTUMMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL2307075 | 0.81 | LMNA (0.45) | NOTUMMEN1KMT2A | |
| SCHEMBL2307114 | 0.80 | BRD4 (0.42) | NOTUMHRH3MEN1KMT2A | |
| SCHEMBL2309105 | 0.76 | CYP1A2 (0.46) | HRH3MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL2310075 | 0.72 | SLC6A4 (0.33) | — | |
| SCHEMBL2306878 | 0.70 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL1920336 | 0.67 | SLC6A4 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1945899 | 0.66 | PDE10A (0.34) | HRH3 | |
| SCHEMBL731968 | 0.66 | LMNA (0.42) | NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039622-B2 | Melanocortin receptor agonists | LG LIFE SCIENCES LTD. (KR) | 2011-10-18 | — | — | US | disclosed |
| US-20110245500-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG CHEM, LTD. (KR) | 2011-10-06 | — | — | US | disclosed |
| US-20110237795-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG CHEM, LTD. (KR) | 2011-09-29 | — | — | US | disclosed |
| US-20110224219-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2011-09-15 | — | — | US | disclosed |
| EP-2350060-A2 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd (KR) | 2011-08-03 | — | — | EP | disclosed |
| US-20100120783-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCE LTD. (KR) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237795-A1 | MELANOCORTIN RECEPTOR AGONISTS | MC1R, MC3R, MC5R | NOTUM 3949/4885HRH3 304/4885MEN1 899/4885 |
| US-20110245500-A1 | MELANOCORTIN RECEPTOR AGONISTS | MC1R, MC3R, MC5R | NOTUM 3949/4885HRH3 304/4885MEN1 899/4885 |
| US-20100120783-A1 | MELANOCORTIN RECEPTOR AGONISTS | MC1R, MC3R, MC5R | NOTUM 3949/4885HRH3 304/4885MEN1 899/4885 |
| US-20110224219-A1 | MELANOCORTIN RECEPTOR AGONISTS | MC1R, MC3R, MC5R | NOTUM 3949/4885HRH3 304/4885MEN1 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.