Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL29155914 | 1.00 | LMNA (0.50) | LMNATSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL235143 | 1.00 | LMNA (0.50) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL719656 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL14762290 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL151893 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL2783417 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL734592 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL176346 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL9847746 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL4623894 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218244-A1 | CURED FILM AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-04 | — | — | US | disclosed |
| US-20240166791-A1 | CURED FILM AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-05-23 | — | — | US | disclosed |
| WO-2024084904-A1 | CURABLE COMPOSITION, CURED FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2024-04-25 | — | — | WO | disclosed |
| EP-4332123-A1 | CURED FILM AND DISPLAY DEVICE | Sumitomo Chemical Company Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| EP-4332122-A1 | CURED FILM AND DISPLAY DEVICE | Sumitomo Chemical Company, Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023189204-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023189203-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023189205-A1 | COMPOSITION, FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023157561-A1 | CURABLE COMPOSITION, CURABLE FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2023-08-24 | — | — | WO | disclosed |
| CN-108387954-B | Laminate, flexible device, and method for producing laminate | 东京应化工业株式会社 | 2022-01-18 | — | — | CN | disclosed |
| WO-2011122707-A1 | COLORED COMPOSITION, INKJET INK, COLOR FILTER AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGE SENSOR AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2011-10-06 | — | — | WO | disclosed |
| EP-1275496-B1 | LAYERED PRODUCT, BONDING METHOD, AND COMPOSITION CURABLE WITH ACTINIC ENERGY RAY | MITSUBISHI CHEM CORP (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20110003241-A1 | RESIN, PIGMENT DISPERSION, COLORED CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND METHOD FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2246385-A1 | RESIN, PIGMENT DISPERSION LIQUID, COLORING CURABLE COMPOSITION, COLOR FILTER PRODUCED BY USING THE COMPOSITION, AND METHOD FOR PRODUCING THE COLOR FILTER | FUJIFILM Corporation (JP) | 2010-11-03 | — | — | EP | disclosed |
| US-20090117330-A1 | ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, EMBOSSED RELEASE SHEET, METHOD FOR MANUFACTURING ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, METHOD FOR MANUFACTURING EMBOSSED RELEASE SHEET, APPARATUS FOR MANUFACTURING EMBOSSED RELEASE SHEET, SYNTHETIC LEATHER, AND METHOD FOR MANUFACTURING SYNTHETIC LEATHER | DAI NIPPON PRINTING CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1992479-A1 | ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, EMBOSSED RELEASE SHEET, METHOD FOR PRODUCING ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, METHOD FOR PRODUCING EMBOSSED RELEASE SHEET, APPARATUS FOR PRODUCING EMBOSSED RELEASE SHEET, SYNTHETIC LEATHER, AND METHOD FOR PRODUCING SYNTHETIC LEATHER | Dainippon Printing Co., Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-20070116929-A1 | Embossed release paper for synthetic leather production and support therefor, and synthetic leather using the release paper and process for producing the synthetic leather | DAI NIPPON PRINTING CO., LTD. (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-1702752-A1 | EMBOSSED RELEASE PAPER FOR PRODUCTION OF SYNTHETIC LEATHER, SUPPORT THEREOF, SYNTHETIC LEATHER UTILIZING THE RELEASE PAPER AND PROCESS FOR PRODUCING THE SAME | Dainippon Printing Co., Ltd. (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-20030118838-A1 | Laminate, adhering method and active energy ray-curable composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1275496-A1 | LAYERED PRODUCT, BONDING METHOD, AND COMPOSITION CURABLE WITH ACTINIC ENERGY RAY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |