Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A known ✓ | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL29155914 | 1.00 | LMNA (0.50) | LMNATSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL230695 | 1.00 | LMNA (0.50) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL719656 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL14762290 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL151893 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL2783417 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL734592 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL176346 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL9847746 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 | |
| Acrylic Acid SCHEMBL4623894 | 0.92 | LMNA (0.59) | LMNATSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218244-A1 | CURED FILM AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-04 | — | — | US | disclosed |
| US-20240166791-A1 | CURED FILM AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-05-23 | — | — | US | disclosed |
| WO-2024084904-A1 | CURABLE COMPOSITION, CURED FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2024-04-25 | — | — | WO | disclosed |
| EP-4332123-A1 | CURED FILM AND DISPLAY DEVICE | Sumitomo Chemical Company Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| EP-4332122-A1 | CURED FILM AND DISPLAY DEVICE | Sumitomo Chemical Company, Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023157561-A1 | CURABLE COMPOSITION, CURABLE FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2023-08-24 | — | — | WO | disclosed |
| CN-108387954-B | Laminate, flexible device, and method for producing laminate | 东京应化工业株式会社 | 2022-01-18 | — | — | CN | disclosed |
| EP-2553025-B1 | COLORED COMPOSITION, INKJET INK, COLOR FILTER AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGE SENSOR AND DISPLAY DEVICE | FUJIFILM CORP (JP) | 2022-01-12 | — | — | EP | disclosed |
| EP-2246385-B1 | RESIN, PIGMENT DISPERSION LIQUID, COLORING CURABLE COMPOSITION, COLOR FILTER PRODUCED BY USING THE COMPOSITION, AND METHOD FOR PRODUCING THE COLOR FILTER | FUJIFILM CORP (JP) | 2017-11-29 | — | — | EP | disclosed |
| CN-104035283-B | Colored composition, ink for inkjet, color filter and its manufacture method and solid-state image sensors and display device | 富士胶片株式会社 | 2017-11-21 | — | — | CN | disclosed |
| EP-1702752-A1 | EMBOSSED RELEASE PAPER FOR PRODUCTION OF SYNTHETIC LEATHER, SUPPORT THEREOF, SYNTHETIC LEATHER UTILIZING THE RELEASE PAPER AND PROCESS FOR PRODUCING THE SAME | Dainippon Printing Co., Ltd. (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-20030118838-A1 | Laminate, adhering method and active energy ray-curable composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1275496-A1 | LAYERED PRODUCT, BONDING METHOD, AND COMPOSITION CURABLE WITH ACTINIC ENERGY RAY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-20020014703-A1 | Semiconductor flip-chip package and method for the fabrication thereof | CAPOTE MIGUEL A (US) | 2002-02-07 | — | — | US | disclosed |
| EP-1001852-A4 | POLYMERIZABLE FLUXING AGENTS AND FLUXING ADHESIVE COMPOSITIONS THEREFROM | AGUILA TECHNOLOGIES INC (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6297560-B1 | Semiconductor flip-chip assembly with pre-applied encapsulating layers | Capote, Miguel Albert | 2001-10-02 | — | — | US | disclosed |
| EP-1001852-A1 | POLYMERIZABLE FLUXING AGENTS AND FLUXING ADHESIVE COMPOSITIONS THEREFROM | Aguila Technologies, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| US-6017634-A | ELECTRICAL COMPONENT BEING ATTACHED TO CARRIER SUBSTRATE THROUGH TERMINAL CONNECTORS JOINED USING INVENTIVE FLUX; LOW MOISTURE ABSORPTION, CORROSION RESISTANCE, NONHYDROLYZING | MIGUEL ALBERT CAPOTE (US) | 2000-01-25 | — | — | US | disclosed |
| US-5985456-A | HEAT CURABLE; NONHYDROLZYING; CORROSION RESISTANCE | Capote, Miguel Albert (US) | 1999-11-16 | — | — | US | disclosed |
| WO-1999003597-A1 | POLYMERIZABLE FLUXING AGENTS AND FLUXING ADHESIVE COMPOSITIONS THEREFROM | AGUILA TECHNOLOGIES, INC. (US) | 1999-01-28 | — | — | WO | disclosed |