Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240149 | 0.79 | CYP1A2 (0.43) | CYP1A2BPTFALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL31118756 | 0.75 | EPHX2 (0.40) | CYP1A2ALDH1A1NFKB1NFKB2RELA | |
| SCHEMBL11471883 | 0.73 | MAPT (0.48) | CYP1A2BPTFALDH1A1KMT2A | |
| SCHEMBL24240163 | 0.72 | EGLN1 (0.41) | CYP1A2BPTFALDH1A1KMT2APANK3 | |
| SCHEMBL24240164 | 0.72 | BPTF (0.39) | CYP1A2BPTFALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL30643765 | 0.72 | BPTF (0.39) | CYP1A2BPTFALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL20075623 | 0.72 | SLC34A1 (0.45) | ALDH1A1GABRB3EPHX2GABRPGABRD | |
| SCHEMBL24253730 | 0.72 | GABRB3 (0.38) | JUNNFKB1NFKB2RELAGABRB3 | |
| SCHEMBL12075244 | 0.72 | EPHX2 (0.45) | ALDH1A1GABRB3EPHX2KMT2ASLC34A1 | |
| SCHEMBL28606131 | 0.71 | TRPV1 (0.43) | JUNNFKB1NFKB2RELAGABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941137-B2 | Difluoromethyl-phenyl triazoles | GABRA5, GABRB1, GABRA1 | CYP1A2 164/4885BPTF 2265/4885ALDH1A1 315/4885 |
| US-20210147393-A1 | DIFLUOROMETHYL-PHENYL TRIAZOLES | GABRA5, GABRB1, GABRA1 | CYP1A2 157/4885BPTF 2248/4885ALDH1A1 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.