Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 7/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.60 |
| ▸ | HTR1A | P08908 | 6/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23072223 | 0.75 | HTR2B (1.00) | HTR2BSIGMAR1HTR1ASLC6A2HTR2C | |
| SCHEMBL23072207 | 0.72 | HTR2B (1.00) | HTR2BSIGMAR1HTR1ASLC6A2HTR2C | |
| SCHEMBL23072225 | 0.71 | HTR2B (1.00) | HTR2BSIGMAR1HTR1ASLC6A2HTR2C | |
| SCHEMBL9749071 | 0.69 | CYP3A4 (0.44) | HTR2BSIGMAR1TMEM97KDM4EMEN1 | |
| SCHEMBL16448789 | 0.69 | CYP3A4 (0.44) | HTR2BSIGMAR1TMEM97KDM4EMEN1 | |
| SCHEMBL7118566 | 0.69 | TMEM97 (0.43) | HTR2BSIGMAR1TMEM97KDM4EMEN1 | |
| SCHEMBL13893989 | 0.67 | MAOA (0.45) | HTR2BSIGMAR1HTR1ATMEM97KDM4E | |
| SCHEMBL23072230 | 0.67 | HTR1A (1.00) | HTR2BSIGMAR1HTR1ASLC6A2HTR2C | |
| SCHEMBL23072233 | 0.67 | HTR2B (0.62) | HTR2BSIGMAR1HTR1ASLC6A2HTR2C | |
| SCHEMBL27570996 | 0.66 | TMEM97 (0.40) | HTR2BSIGMAR1SLC6A2HTR2CTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941153-B2 | Substituted phenethylamine derivatives | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941153-B2 | Substituted phenethylamine derivatives | PNMT, PRMT1, PRMT3 | HTR2B 124/4885SIGMAR1 97/4885HTR1A 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.