Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791872 | 1.00 | IDO1 (0.46) | IDO1HTR1ASLC6A4CYP11B1CYP11B2 | |
| SCHEMBL6603605 | 0.86 | APLNR (0.44) | IDO1CYP11B1CYP11B2ADRA1ATAAR1 | |
| SCHEMBL500774 | 0.85 | IDO1 (0.41) | IDO1HTR1ASLC6A4ADRA1ATAAR1 | |
| SCHEMBL30108669 | 0.85 | IDO1 (0.43) | IDO1HTR1ASLC6A4ADRA1ATAAR1 | |
| SCHEMBL14270259 | 0.85 | IDO1 (0.43) | IDO1HTR1ASLC6A4ADRA1ATAAR1 | |
| SCHEMBL7551792 | 0.83 | ADRA1A (0.48) | IDO1HTR1ASLC6A4ADRA1ATAAR1 | |
| SCHEMBL8259521 | 0.82 | SLC6A4 (0.41) | HTR1ASLC6A4 | |
| SCHEMBL1058869 | 0.82 | HTR2A (0.44) | IDO1HTR1ASLC6A4ADRA1ATAAR1 | |
| SCHEMBL2001551 | 0.82 | HSD17B10 (0.44) | IDO1HTR1ASLC6A4ADRA1ATAAR1 | |
| SCHEMBL31348890 | 0.81 | HTR1A (0.41) | IDO1HTR1ASLC6A4ADRA1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051102-A1 | DEUTERATED TETRACYCLIC DERIVATIVE AND USE THEREOF | 浙江我武翼方药业有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119591611-A | Deuterated tetracyclic derivative and application thereof | 浙江我武翼方药业有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-118146234-A | 6,5,7,6-Tetracyclic derivatives, preparation method and application thereof | 浙江我武翼方药业有限公司 | 2024-06-07 | — | — | CN | disclosed |