Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073295 | 0.78 | LMNA (0.39) | ADRB2KDM1A | |
| SCHEMBL15078792 | 0.73 | LMNA (0.53) | ADRB2KDM1A | |
| SCHEMBL23073296 | 0.65 | LMNA (0.52) | ADRB2KDM1A | |
| SCHEMBL23073289 | 0.63 | KDM1A (0.35) | KDM1A | |
| SCHEMBL17088062 | 0.61 | ABCB11 (0.53) | — | |
| SCHEMBL11525607 | 0.60 | VCAM1 (0.39) | — | |
| SCHEMBL11685893 | 0.60 | ALDH1A1 (0.37) | — | |
| SCHEMBL24670355 | 0.56 | — | — | |
| SCHEMBL19175432 | 0.56 | KDM1A (0.44) | KDM1A | |
| SCHEMBL29802422 | 0.56 | VCAM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793872-B1 | COMBINATION OF A COMPOUND HAVING THE ABILITY TO REARRANGE A LYSOSOMAL ENZYME AND AMBROXOL AND/OR A DERIVATIVE OF AMBROXOL | CENTOGENE IP GMBH (DE) | 2021-03-10 | — | — | EP | disclosed |