Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23073659 | 0.86 | GPR119 (0.53) | LMNAKMT2ASMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL707999 | 0.86 | LMNA (0.56) | LMNAS1PR2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20339473 | 0.86 | SMN1; SMN2 (0.52) | LMNAS1PR2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27202624 | 0.85 | L3MBTL1 (0.56) | LMNAS1PR2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30019168 | 0.83 | S1PR2 (0.48) | LMNAS1PR2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL25093937 | 0.83 | S1PR2 (0.48) | LMNAS1PR2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28008432 | 0.82 | SMN1; SMN2 (0.50) | LMNAKMT2ASMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL3846595 | 0.82 | ESR2 (0.51) | LMNAKMT2ASMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL24992422 | 0.81 | NR1H2 (0.52) | LMNAKMT2ASMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL3856804 | 0.80 | ALDH1A1 (0.52) | LMNAKMT2ASMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562822-B1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | MITOBRIDGE INC (US) | 2021-03-10 | — | — | EP | disclosed |