Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2351409 | 0.99 | HTR2A (0.51) | HTR2ASLC6A9ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23074697 | 0.91 | HTR2A (0.47) | HTR2ASLC6A9ALDH1A1HRH3KDM4E | |
| SCHEMBL2352960 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL8060867 | 0.80 | SLC6A2 (0.50) | HTR2AKDM4ESMN1; SMN2 | |
| SCHEMBL23074674 | 0.79 | HRH3 (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C19HRH3 | |
| SCHEMBL23074644 | 0.79 | KDM4E (0.51) | ALDH1A1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL2351615 | 0.77 | SMN1; SMN2 (0.41) | HTR2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2353380 | 0.76 | SMN1; SMN2 (0.40) | HTR2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL23074687 | 0.76 | SLC6A9 (0.42) | HTR2ASLC6A9ALDH1A1CYP2D6 | |
| SCHEMBL2355188 | 0.75 | GRIN2B (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257225-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | M'S SCIENCE CORPORATION (JP) | 2011-10-20 | — | — | US | claimed |
| CN-102197017-A | Phenyl-containing cyclohexylamine derivatives and remedies for central nervous system disorder-associated diseases | MS SCIENCE CORP | 2011-09-21 | — | — | CN | claimed |
| EP-2357165-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | M's Science Corporation (JP) | 2011-08-17 | — | — | EP | claimed |
| US-20110257225-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | M'S SCIENCE CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110257225-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | M'S SCIENCE CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110257225-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | M'S SCIENCE CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| CN-102197017-A | Phenyl-containing cyclohexylamine derivatives and remedies for central nervous system disorder-associated diseases | MS SCIENCE CORP | 2011-09-21 | — | — | CN | disclosed |
| EP-2357165-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | M's Science Corporation (JP) | 2011-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257225-A1 | CYCLOHEXYLAMINE DERIVATIVE CONTAINING PHENYL GROUP, AND THERAPEUTIC AGENT FOR DISEASES ACCOMPANIED BY CENTRAL NERVOUS SYSTEM DISORDERS | SIGMAR1, OPRM1, OPRK1 | HTR2A 19/4885SLC6A9 1188/4885ALDH1A1 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.